Kel, you'll find that the pushrods, tappets, and cam interface will wear (alarmingly) at first, and you'll be adjusting valve clearance for a while, but then suddenly everything seems to calm down, and you'll not have to mess with it so much.
I made my radial engine so that clearance was done by having adjustable pushrods rather than rocker arms, but the principle is the same. The engine breaks in, and then there is much less adjusting of these components.
The problem with IC engines is that every time you run them, you'll find something that needs tweaking. Worst is the phenomenon of a cylinder no longer firing, along for the ride, with the others powering the engine. VERY annoying, and you'll stop at nothing to fix it!
Enjoy!