I suggest this engine configuration is most advantageous as a 2-stroke, such as the Deltic & T3 already mentioned, where ports at opposite ends provide excellent scavenging, especially with a blower.
The arrangement is is also useful for research, as an eccentric mounting of the rocker shaft allows simple adjustment of the compression ratio.
As a 4-stroke I don't see anything much to recommend it, other than it is slightly oddball. But hey, you're doing it, not me.
BTW if you are not familliar with them, Deltics in particular have a wonderfully distinctive sound:
[ame]http://www.youtube.com/watch?v=ggm1YVith44[/ame]
the Commer is distinctive too:
[ame]http://www.youtube.com/watch?v=e0sLp7wvq60[/ame]