Hi, Brian. At very low speed, say about the 30 rpm mark with no load, the the lack of balance might well show, but at that sort of speed I would think variations in friction and leakage would have just as much of an effect on smooth running. At a normal low speed, I think you would be better off at 90° especially with o-rings on the pistons: the torque will be much more constant with four small power pulses instead of two big ones. At higher speed (the bits become blurry at 200-250 rpm) there would indeed be a bit less vibration at 180°, though there would still be a rocking couple. 180° is very abnormal for a double-acting twin - with good reason?