Jim et al,
Just to clarify, I don't think I have ever had the valve itself clog from paint. However, depending somewhat on the kind of paint, I have had what I feel was dried paint inside the valve stem come loose from the action of the solvent in the new paint coming through the valve. This material is transferred to the spray orifice by the flow of fresh paint and instant clog results. The symptom is spraying starts out OK and abruptly stops before you're finished. As a side note to using the brake cleaner, I think the pressure of the brake cleaner that I have is higher than the pressure in the spray cans I have so, sometimes, it can blow out a clog that the paint can itself cannot do. Wear glasses or a face shield with the brake cleaner. It tends to go in unexpected directions.