One of the nice things about York is the wide range of food and lodging within just a few miles of the show. If you look at a map rt 30 makes an arc, kind of a half beltway, round the north of York. Along that road are dozens of hotels, from the cheapest Motel 6 and up. Just ask Google and you will find everything you want.
The somewhat 'official' hotel of the show is the Holiday Inn "Holidome' on Loucks Rd. It is probably the closest to the show, but also probably the most expensive. It does have very nice rooms, restaurants and bars. There have been found many guys up much to late solving the worlds problems at the bar. Note that I only know this because I have been told about it, not because I stayed up to late talking.
If you like the old style hotel there is one right in the center of York, a classic 1920 or so place. I have not stayed there, but I have had dinner and it was a very fine, quiet place.
BTW- York has a very nice main street historical area that would be fun to tour, with some interesting shops etc. I know guys that have had a wife/SO with them that have spent a day along there. Rt 30 is also end to end shopping centers for the more conventional shoppers.
Not only is Cabin Fever a great show, York is a nice place to visit. A couple things I have enjoyed is the Harley Davidson plant tour and a visit to the National watch and Clock Museum in Columbia, about 15 miles east of York. Also the York Musuem of Industry where past Cabin fever receptions have been held.