Hi guys. Just a few odd comments - based on experience with single carb car engines in the Manufacturer's design office.
One of the things that affects petrol (and other "wet" fuels) and air mixtures is the simple dynamics is a column of gas withe "wert" droplets in it. The gas goes around corners, but the droplets don't.., (Newton's laws of motion - Laws we can't avoid!) so the "wet" goes straight on and doesn't all turn the corner with the gas (air and vapour). Carburettors give a mixture of air plus fuel vapour, Aerosols (very fine droplets) and "wet droplets".
So consider a single carb feeding a single cylinder. When the valve opens, the air column accelerates, and as the accelerating air increases velocity in the carb it starts to draw up droplets of fuel. - Related to the square of the speed of air in the throat of the carb.... Initially the speed of air in the carb is too low to shred the droplets into smaller "aerosols" and heat has to flow into the aerosols to turn them from liquid to vapour.
(Hmmm.... getting a bit complicated, so I'll carefully describe the next steps):
When the carb is at "full gas flow" for the wide-open engine valve and mid-stroke of the piston, whatever the throttle valve is set at, there is a good amount of aerosol (and a bit of vapour) and not so much as "wet" droplets.
Then as the inlet valve closes, the column of gas slows, so we get more droplets against less aerosol fuel.
The combustion chamber heats the mix of air, aerosol fuel, vaporising some of the aerosol, and heating the droplets.
The spark ignites a fuel-air mix of vapour and oxygen in a volume of nitrogen.... and when correct the flame heats the aerosol further to assist igniting all the mixture. But (especially at higher engine speeds) the droplets don't all burn, just the "outer-part" so there is some residual hydro-carbon in the exhaust. - We have all seen the soot on older cars, even when we think the mixture is correct. What the plugs show is the mixture that has burned - at least as far as Carbon monoxide, not the results of all the fuel burning completely. Modern fuel injected engines with O2 sensors correct this "impossible process" from carburettors.
Now consider a manifold with centre carb and 2 legs going left and 2 to the right to feed 4 cylinders. - We will discuss one half. Say cylinders 1 and 2. These fire at some spacing, not necessarily 360 degrees apart on the crank - so maybe inlet of one, - then 180degrees crank - to inlet of next... then 240 degrees to inlet of the first? Oops! Sounds like we cannot expect the columns of air to have the same starting conditions when the inlet valve opens. - This imbalances the air per cylinder and thus the mixture.
But what about the fuel as it travels along a z-shaped passage to the valve? Going to the furthest cylinder, the droplets try and go straight on at the end of the manifold, instead of following the turn made by the air and aerosols into the cylinder. These droplets hit the inside of the end if the manifold, and eventually get sucked into the engine as larger, but hotter, droplets. That does NOT help good combustion of that bit of fuel. So we need a richer mixture to compensate for that "loss" of combustible fuel. (It probably burns in the exhaust pipe, not the cylinder!). But consider the column of air and aerosol to the nearest cylinder to the carb? The air and aerosol turning from the manifold to the inlet tract to valve and cylinder allows a lot of the fuel droplets to fly past the inlet tract and hang around in the relatively still air at the next cylinder inlet tract... (furthest from the carb). So Middle cylinders are thus starved of some of their fuel, which goes towards the outer cylinders...
Hence, we have a lot of factors that affect the individual mixtures in cylinders:
# Effect of a "stopped" column of gas accelerating to sucking adequate aerosol-fuel for the engine to run but getting droplets of "excess" fuel when the gas column is slow at the start.
# Imbalance of position of each cylinder "sucking" in degrees around the crankshaft = different "dwell times" between valve openings.
# Imbalances of position of cylinder along the length of manifold.
And in truth it is more complicated than that!
I worked alongside an engineer who's job was to make the inlet manifold castings with internal vanes to direct the fuel and air mix around the corners, to try and correct the "droplet" problems. - These problems "disappeared" when the manifold only had to carry air, because the fuel was injected at the inlet tract close to the inlet valve.
So "well done" anyone who manages to make a multi-cylinder engine with unequal inlets through the manifold run smoothly.
I hope I have not made this either too simple or too complicated for you? It really is more complicated than I describe when tuning production engines for the optimum performance and to meet emission laws.
K2